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Diazepam is N-demethylated by CYP3A4 and 2C19 for the Energetic metabolite N-desmethyldiazepam, which is hydroxylated by CYP3A4 for the Lively metabolite temazepam. N-desmethyldiazepam and temazepam are both equally additional metabolized to oxazepam. Temazepam and oxazepam are largely eliminated by glucuronidation.An increased hazard of congenital